Platelets

Platelets, a vital component of blood, are primarily responsible for cessation of bleeding by forming blood clots.  When removed from the blood stream and subjected to component manufacturing, platelets natural response is to form clots. Manufacturing and storage processes are designed to keep the platelets from clumping together and to keep them viable by strict room temperature requirements and continual agitation. Even with this care, the transfusion products only have a 5-day shelf life.  With such a short shelf life, comes high demand for donations of platelets. Platelet apheresis donors, providing up to three doses of platelets per donation, typically donate more than 6 times a year and are committed to sitting for 1 to 2 hours per donation.

BCA member sites provide platelets to:

  • Hospitals for patient care. Patients lacking adequate number of platelets can experience spontaneous bruising and bleeding. Platelets are most often transfused to trauma patients or to cancer and leukemia patients undergoing therapies that depress the production of platelets in the bone marrow.
  • Biotech companies using platelets as a component of their therapeutic compounds.  For example, platelets are often used in wound healing products.
  • Therapeutic or life science companies using platelets as an ancillary production component.
  • Device, diagnostic or drug companies using platelets for research and development.

Where a client’s need exceed what can be provided by a single source, BCA assist clients with identifying and securing a sufficient supply from multiple sources under a single contract.  If you are interested in discussing your platelet procurement or provision needs with BCA, please contact Gena Swisher.

BCA members provide the following types of platelets though modifications in production, volume, storage, and age can be made to produce the ideal product for further manufacture or research and development:

Apheresis Platelets

  • Collected from a single donor connected to apheresis equipment
  • Anticoagulant: ACD-A
  • Volume: 200 – 400ml
  • Contains minimum of 3.0 x 1011 platelets
  • Stored: 20 – 24°C
  • Shelf-life: 5 days

Whole Blood Platelets

  • Derived from Whole Blood collection
  • Volume: 40 – 65ml
  • Contains minimum of 5.5 x 1010 platelets
  • Stored: 20 – 24°C
  • Shelf-life: 5 days

Pooled Platelets – 5d

  • 3 to 6 Whole Blood Platelets pooled in a patented system for 5 day shelf-life
  • Volume: 150 – 400ml
  • Contains minimum of 3.0 x 1011 platelets
  • Stored: 20 – 24°C
  • Shelf-life: 5 days

For more information about BCA’s capabilities please contact Gena Swisher.