BloodCenter of Wisconsin and Eastman Chemical Company announce new blood bag clinical trial results

Study supports viable alternative for blood bag plasticizers

Kingsport, Tenn., November 14, 2016 — BloodCenter of Wisconsin (BCW, part of Versiti) and Eastman Chemical Company (NYSE:EMN) have announced the results of a recent clinical trial evaluating a new plasticizer for blood bags. While di-2-ethylhexyl phthalate (DEHP) has provided the medical industry with a stable ortho-phthalate plasticizer for many years, regulatory trends and consumer demands will inevitably drive the industry to non-phthalate alternatives. The clinical trial results demonstrate that Eastman 168™ SG non-phthalate plasticizer, a sensitive-grade DEHT, is a viable alternative for medical applications.

“Blood bags are one of the most challenging applications in the plastics market,” says Eastman Market Development Manager Mark Brucks. “BCW’s research is important because it demonstrates a viable alternative for those who have concerns around using DEHP in sensitive applications like blood bags, and it’s also a testament to the importance of material suppliers and institutions working together to find safer solutions.”

The clinical trial findings were presented at the 2016 AABB Annual Meeting in Orlando, Florida, on Oct. 24 by Sharon Graminske, manager of applied research laboratory at BloodCenter of Wisconsin. Entitled “In Vitro Evaluation of DEHT Plasticized PVC Blood Bags for Red Blood Cell Storage in AS-1 and PAGGSM Preservative Solutions,” Graminske’s presentation highlighted the trend driving the need for DEHP alternatives as well as the preliminary results supporting DEHP replacement with DEHT, a non-phthalate general-purpose plasticizer.
“Our work with Eastman has provided valuable results that will benefit the blood banking industry,” said Kathleen Puca, M.D., BloodCenter medical director and principal investigator who oversaw the findings reported by Graminske. “The DEHT trial results offer new insight about a well-established plasticizer that has now been proven to have an even broader application within health care — providing safer blood products.”

Further work is being completed on plasma to validate performance. “Eastman 168 SG is a proven, tested, and toxicologically clean solution for the medical market,” says Brucks. “By working closely with BCW, we are able to extend the utility of Eastman 168 SG into this application, offering customers a cost-effective alternative that performs to standard so that they can confidently make the switch from DEHP when they are ready.”

BloodCenter of Wisconsin’s Clinical Trials and Cellular Therapy Services provide a full spectrum of services for clinical trials (preclinical and phases I–IV) in a wide range of therapeutic areas. BloodCenter of Wisconsin has assisted pharmaceutical and medical device companies with regulatory studies, laboratory testing, assay development and a variety of other research needs for more than 30 years.

For more information on products enabling flexibility in the medical market, visit www.EastmanPlasticizers.com.

About Blood Center of Wisconsin
BloodCenter of Wisconsin, part of Versiti, is a not-for-profit organization headquartered in Milwaukee, Wis., that specializes in blood services; diagnostic testing; organ, tissue and marrow donation; medical services and leading-edge research. We advance patient care by delivering life-saving solutions grounded in unparalleled medical and scientific expertise. The collective efforts of Versiti affiliates result in improved patient outcomes, expanded access to care and cost efficiencies for health care systems nationwide. For more information, visit www.bcw.edu and www.versiti.org.
About Eastman
Eastman is a global specialty chemical company that produces a broad range of products found in items people use every day. With a portfolio of specialty businesses, Eastman works with customers to deliver innovative products and solutions while maintaining a commitment to safety and sustainability. Its market-driven approaches take advantage of world-class technology platforms and leading positions in attractive end markets such as transportation, building and construction, and consumables. Eastman focuses on creating consistent, superior value for all stakeholders. As a globally diverse company, Eastman serves customers in approximately 100 countries and had 2015 revenues of approximately $9.6 billion. The company is headquartered in Kingsport, Tennessee, USA, and employs approximately 15,000 people around the world. For more information, visit www.eastman.com.

Solera Health and Blood Centers of America Align To Deliver National Diabetes Prevention Program to Patients at the Hyper-Local Level

West Warwick, RI and Phoenix, AZ-October 31, 2016– Blood Centers of America (BCA) and Solera Health, an integrator of chronic disease prevention and management solutions, today announced they have entered into a strategic partnership to address the type 2 diabetes epidemic by implementing diabetes prevention and management programs to reach individuals across the diverse landscape of BCA’s service area. Under the terms of the agreement, BCA and its members will join Solera’s integrated network of partners who are working towards preventing and managing chronic disease.
BCA’s Diabetes Prevention Program (DPP) was built with the goal of engaging their community population to get more involved in their health and to take the necessary steps to make healthy lifestyle changes to maintain or improve their health. The chronic disease prevention initiative, which is expected to initially launch in BCA blood centers located in California, and then expand to its network of 300+ fixed site locations across the country. Click Here to Read More.

BLOOD CENTERS OF AMERICA JOINS COUNCIL FOR DIABETES PREVENTION

West Warwick, RI, October 7, 2016– Blood Centers of America is pleased to announce its membership in the recently formed Council for Diabetes Prevention to support the delivery of the Centers of Disease Control National Diabetes Prevention Program.
“BCA and its members are uniquely positioned to deploy the National Diabetes Prevention Program by leveraging our diverse footprint, mobility and our long standing trust in the communities we serve. This provides us an additional opportunity to better serve and support our donor population as well as the communities that have established many of our blood centers.”
-Bill Block, President/CEO Blood Centers of America
The Council for Diabetes Prevention brings together industry stakeholders to increase access to the National Diabetes Prevention Program, promote high-quality standards, and support the long-term scalability and sustainability of this unique patient-centric, community-based program.
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San Diego Blood Bank and the National Blood Collaborative receive Sub-award to support the U.S. Precision Medicine Initiative Cohort Program

SAN DIEGO, CA – October 3, 2016 – As part of the most ambitious medical research program
in the history of American medicine, the San Diego Blood Bank (SDBB) and the National Blood
Collaborative (NBC) have received a sub-award for their role in enrolling participant-volunteers
into the national Precision Medicine Initiative (PMI) Cohort Program.

Click Here to Read More SDBB PMI news

Martin Landon Named CEO of BioBridge Global

SAN ANTONIO – Longtime biomedical industry executive Martin Landon has been named chief executive officer of BioBridge Global (BBG), the nonprofit organization that oversees and supports the South Texas Blood & Tissue Center (STBTC), QualTex Laboratories, GenCure and The Blood & Tissue Center Foundation. The announcement was made today by BBG Board Chair Mike Kreager. Click Here for more

IPFA /BCA 3rd Global Symposium on The Future for Blood and Plasma Donations 11 – 12 September 2017 | Atlanta, GA, USA

The International Plasma Fractionation Association (IPFA) and Blood Centers of America (BCA) are pleased to announce the 3rd Global Symposium on the Future for Blood and Plasma Donations. This Symposium will build on the success of the 2014 and 2015 meetings, which highlighted the increasing global need for plasma derived medicinal products and identified opportunities for Blood Centers to contribute to this need. Each meeting attracted about 180 delegates from throughout the USA and other countries. We have received excellent feedback from delegates to these meetings.

Key issues
This third Symposium will continue to develop the theme of plasma supply. Hosted by Blood Assurance, a non-profit, full-service regional blood center serving 51 counties and more than 70 health care facilities in Tennessee, Georgia, Alabama, North Carolina and Virginia, a comprehensive range of topics will be addressed including:
• Clinical developments in plasma product use
• Plasma supply – optimizing plasma collection and economics
• Donor recruitment
• Industry developments in support of blood establishments
• Keeping donors and plasma safe
• Regulatory issues
• Quality management of plasma

For more information, please click IPFA Events 2017

San Diego Blood Bank and BloodCenter of Wisconsin form new cellular therapy partnership

Combining their expertise in clinical trials support and cellular therapies, BloodCenter of Wisconsin (BCW) and the San Diego Blood Bank (SDBB) have created a strategic partnership to accelerate advancements in research and patient care. Together, BloodCenter of Wisconsin and San Diego Blood Bank will offer Celluvative™ – a portfolio of products and clinical trial services that will include esoteric laboratory testing, blood products for research and manufacturing applications, cell processing, and access to a broad database of diverse donors who have expressed interest in clinical trials.
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