Study supports viable alternative for blood bag plasticizers
Kingsport, Tenn., November 14, 2016 — BloodCenter of Wisconsin (BCW, part of Versiti) and Eastman Chemical Company (NYSE:EMN) have announced the results of a recent clinical trial evaluating a new plasticizer for blood bags. While di-2-ethylhexyl phthalate (DEHP) has provided the medical industry with a stable ortho-phthalate plasticizer for many years, regulatory trends and consumer demands will inevitably drive the industry to non-phthalate alternatives. The clinical trial results demonstrate that Eastman 168™ SG non-phthalate plasticizer, a sensitive-grade DEHT, is a viable alternative for medical applications.
“Blood bags are one of the most challenging applications in the plastics market,” says Eastman Market Development Manager Mark Brucks. “BCW’s research is important because it demonstrates a viable alternative for those who have concerns around using DEHP in sensitive applications like blood bags, and it’s also a testament to the importance of material suppliers and institutions working together to find safer solutions.”
The clinical trial findings were presented at the 2016 AABB Annual Meeting in Orlando, Florida, on Oct. 24 by Sharon Graminske, manager of applied research laboratory at BloodCenter of Wisconsin. Entitled “In Vitro Evaluation of DEHT Plasticized PVC Blood Bags for Red Blood Cell Storage in AS-1 and PAGGSM Preservative Solutions,” Graminske’s presentation highlighted the trend driving the need for DEHP alternatives as well as the preliminary results supporting DEHP replacement with DEHT, a non-phthalate general-purpose plasticizer.
“Our work with Eastman has provided valuable results that will benefit the blood banking industry,” said Kathleen Puca, M.D., BloodCenter medical director and principal investigator who oversaw the findings reported by Graminske. “The DEHT trial results offer new insight about a well-established plasticizer that has now been proven to have an even broader application within health care — providing safer blood products.”
Further work is being completed on plasma to validate performance. “Eastman 168 SG is a proven, tested, and toxicologically clean solution for the medical market,” says Brucks. “By working closely with BCW, we are able to extend the utility of Eastman 168 SG into this application, offering customers a cost-effective alternative that performs to standard so that they can confidently make the switch from DEHP when they are ready.”
BloodCenter of Wisconsin’s Clinical Trials and Cellular Therapy Services provide a full spectrum of services for clinical trials (preclinical and phases I–IV) in a wide range of therapeutic areas. BloodCenter of Wisconsin has assisted pharmaceutical and medical device companies with regulatory studies, laboratory testing, assay development and a variety of other research needs for more than 30 years.
For more information on products enabling flexibility in the medical market, visit www.EastmanPlasticizers.com.
About Blood Center of Wisconsin
BloodCenter of Wisconsin, part of Versiti, is a not-for-profit organization headquartered in Milwaukee, Wis., that specializes in blood services; diagnostic testing; organ, tissue and marrow donation; medical services and leading-edge research. We advance patient care by delivering life-saving solutions grounded in unparalleled medical and scientific expertise. The collective efforts of Versiti affiliates result in improved patient outcomes, expanded access to care and cost efficiencies for health care systems nationwide. For more information, visit www.bcw.edu and www.versiti.org.
Eastman is a global specialty chemical company that produces a broad range of products found in items people use every day. With a portfolio of specialty businesses, Eastman works with customers to deliver innovative products and solutions while maintaining a commitment to safety and sustainability. Its market-driven approaches take advantage of world-class technology platforms and leading positions in attractive end markets such as transportation, building and construction, and consumables. Eastman focuses on creating consistent, superior value for all stakeholders. As a globally diverse company, Eastman serves customers in approximately 100 countries and had 2015 revenues of approximately $9.6 billion. The company is headquartered in Kingsport, Tennessee, USA, and employs approximately 15,000 people around the world. For more information, visit www.eastman.com.
The Blood Center & Tissue of Central Texas has changed its name to We Are Blood. You can get the inside story on the brand new blog.
A four-organization biotech group led by San Antonio-based nonprofit BioBridge Global (BBG) has been awarded a $7.8 million contract from the Medical Technology Enterprise Consortium (MTEC). The funds will enable the development of large-scale manufacturing capabilities for clinical-grade stem cells for research and therapeutic use. Click Here to Read More>>
SAN DIEGO, CA – October 3, 2016 – As part of the most ambitious medical research program
in the history of American medicine, the San Diego Blood Bank (SDBB) and the National Blood
Collaborative (NBC) have received a sub-award for their role in enrolling participant-volunteers
into the national Precision Medicine Initiative (PMI) Cohort Program.
Click Here to Read More SDBB PMI news
SAN ANTONIO – Longtime biomedical industry executive Martin Landon has been named chief executive officer of BioBridge Global (BBG), the nonprofit organization that oversees and supports the South Texas Blood & Tissue Center (STBTC), QualTex Laboratories, GenCure and The Blood & Tissue Center Foundation. The announcement was made today by BBG Board Chair Mike Kreager. Click Here for more
OKLAHOMA CITY – Air ambulances are often the first line of treatment for Oklahomans who suffer traumatic injuries during an accident. Read More >>
Combining their expertise in clinical trials support and cellular therapies, BloodCenter of Wisconsin (BCW) and the San Diego Blood Bank (SDBB) have created a strategic partnership to accelerate advancements in research and patient care. Together, BloodCenter of Wisconsin and San Diego Blood Bank will offer Celluvative™ – a portfolio of products and clinical trial services that will include esoteric laboratory testing, blood products for research and manufacturing applications, cell processing, and access to a broad database of diverse donors who have expressed interest in clinical trials.
For Greenville’s Shriners Hospitals for Children
Piedmont, SC (March 7, 2016) – The Blood Connection and Shriners Hospitals for Children—Greenville have announced a new service partnership. Before a patient receives a life-saving blood transfusion, a routine series of laboratory tests determine patient and donor compatibility. Previously, Greenville Shriners Hospital, like many hospitals, performed these tests on-site and used TBC’s Immunohematology Reference Laboratory for research as needed to resolve incompatibilities. Now, all transfusion services for the hospital will be performed by TBC’s Reference Laboratory.
“Last summer, we began working with TBC on a plan to support the hospital’s transfusion needs,” said Administrator Randy Romberger. “TBC has long been our supplier of blood products and we realized it made sense to access the vast testing and reference resources offered through its Biologics Processing Center. Combining these services will give us new efficiencies that support and enhance our high standard of patient care.”
Each time a patient needs a blood transfusion, a series of standard tests decreases the risk of a transfusion reaction. Blood typing is the first step and this determines whether a patient has A, AB, B or O-type blood. This is followed by another test that determines a patient’s Rh type, either negative or positive, so that a compatible donation from a blood donor can be selected. Cross matching is the final step, where a sample of a donor’s blood is combined with a patient’s blood and observed for compatibility.
“TBC has always served as the supplier for blood products at Shriners Hospitals for Children, but compatibility testing was performed by hospital staff,” said TBC President and CEO Delisa English. “This is the first time TBC has partnered with a hospital to provide all of these transfusion services and it’s a natural progression of services. We’re pleased to be able to provide this biomedical solution.”
About The Blood Connection
Founded in 1979 in Greenville, SC, The Blood Connection (TBC) is the largest independently managed, non-profit community blood center in the region. It recruits donors and collects blood within an 8,390 square mile area of South Carolina, Georgia and North Carolina. In South Carolina, TBC supports Greenville, Spartanburg, Union, Pickens, Oconee, Greenwood, McCormick, Laurens, and Newberry Counties. In Georgia, TBC supports Stephens County. In 2011, The Blood Connection expanded into Western North Carolina and now serves Polk, Buncombe, Transylvania, McDowell, Macon and Henderson Counties.
Licensed and regulated by the U.S. Food and Drug Administration, TBC collects blood from donors through bloodmobiles, portable field units, and fixed donation sites. It holds approximately twelve blood drives every day and collects over 120,000 units of blood, platelets and plasma each year to connect volunteer blood donors, hospitals, and patients needing life-saving transfusions. For more information, visit thebloodconnection.org.
About Shriners Hospitals for Children—Greenville
Shriners Hospitals for Children – Greenville provides specialty orthopedic care and services, regardless of ability to pay. Children up to age 18 are eligible for care at Shriners Hospitals for Children if, in the opinion of our physicians, there is a reasonable possibility the child can benefit from the specialized services available. Acceptance is based solely on a child’s medical needs. For more information, visit www.GreenvilleShrinersHospital.org.
Ward Carter has held various roles at Abbott Laboratories
SAN ANTONIO – Health care industry veteran Edward (Ward) Carter has been named the new chief operating officer for QualTex Laboratories, effective immediately.
He will replace Dirk Johnson, who announced his departure late last year. Johnson will stay with QualTex through March to assist with the transition.
Carter was selected after a nationwide search, said Linda Myers, chief executive officer of BioBridge Global, parent organization of QualTex Laboratories.
“Ward has been intensively customer-focused throughout his career, building relationships with businesses from coast to coast,” Myers said. “He is closely aligned with our commitment to increasing our levels of customer service across the organization.”
Carter, a graduate of Stephen F. Austin State University, worked for more than 30 years in the diagnostics division at Abbott Laboratories. His most recent position was as director of strategic products, inventory manager at Abbott Diagnostics Division U.S. commercialization.
His roles at Abbott Laboratories included extensive work with QualTex Laboratories, in various roles. He started with Abbott in sales 1984, and in 2011 he received the company’s Chairman’s Award, the highest the company bestows on its employees.
“I am thrilled to be joining an organization like BioBridge Global and QualTex Labs,” Carter said. “We’re poised for significant growth throughout the enterprise, and especially in QualTex.”
QualTex Laboratories is one of the largest independent nonprofit testing centers in the United States, performing advanced testing services for blood, plasma and tissue donations, as well as reference testing and clinical research.
With laboratories in San Antonio and Norcross, Ga., QualTex tests millions of samples for clients around the world every year.
About QualTex Laboratories: QualTex Laboratories is a nonprofit affiliate of BioBridge Global that provides state-of-the-art biologic testing services on whole blood, plasma and human cells, tissue, and cellular- and tissue-based products (HCT/P) for its global biotechnology and biopharmaceutical customers. It’s one of the nation’s largest nonprofit testing laboratories and has locations in Texas and Georgia. Visit us at qualtexlabs.org.
About BioBridge Global: BioBridge Global (BBG) is a San Antonio, Texas-based nonprofit corporation that offers diverse services through its subsidiaries – the South Texas Blood & Tissue Center, QualTex Laboratories, GenCure and the Blood & Tissue Center Foundation. BBG provides products and services in blood resource management, cellular therapy, donated umbilical cord blood and human tissue as well as testing of blood, plasma and tissue products for clients in the United States and worldwide. BBG is rooted in the South Texas Blood & Tissue Center, which has a proud history of serving the South Texas region and beyond for more than 40 years. BBG is committed to supporting groundbreaking research, addressing unmet clinical needs and enabling the development and commercialization of novel biotechnology products. Visit us at www.biobridgeglobal.org.